For many people, shingles is an afterthought — a painful rash that happens to other people. But the reality is far more serious with about one in three adults developing shingles in their lifetime.1 For some, the characteristic painful rash is just the beginning. Lasting consequences, which are often underestimated, can include severe and persistent nerve pain, burning, and itching that continue long after the rash has subsided. Recognizing the full impact of this disease is key to understanding why prevention through vaccination is a critical component of healthy aging, particularly for those over 50 or with a weakened immune system.
More than "just a rash"
Shingles is caused by the same virus that causes chickenpox, the varicella-zoster virus. According to the CDC, more than 99% of Americans born before 1980 have had chickenpox, even if they do not remember it.1 After a person recovers from chickenpox, the virus remains dormant in the body and can reactivate years later and cause shingles. When it does reactivate, the effects can be severe.
"Shingles can lead to intense pain, complications like nerve damage, and even hospitalization," said Samantha Picking, PharmD, senior director of immunizations at Walgreens. "One of the most common complications of shingles is postherpetic neuralgia, a condition that can cause persistent, burning nerve pain long after the rash disappears. For some, this pain can interfere with sleep, work, and everyday activities, lasting months or even years."
The best defense is prevention
While shingles can have a serious impact, it is also highly preventable. The CDC recommends two doses of the shingles vaccine for adults ages 50 and older, as well as for adults 19 and older with weakened immune systems.2 Studies show the vaccine is 97% effective at preventing shingles in adults 50-69 years old with healthy immune systems and 91% effective at preventing postherpetic neuralgia.
Some people may experience mild side effects after vaccination, but these typically go away within a few days.
"While some individuals may feel some discomfort after getting the shingles vaccine, such as a sore arm or fatigue, it is far less than the pain and potential complications associated with a shingles infection," said Picking.
Additionally, most insurance plans, including Medicare Part D and many private health insurance providers, cover shingles vaccines, making it accessible and often free for eligible individuals.
Beyond shingles: Other important vaccines for older adults
Staying up to date on all your routine vaccinations is one of the easiest ways to protect your health as you age.
"Beyond shingles, I recommend asking your pharmacist about additional routine vaccinations that are vital for healthy aging — it is about proactive health, not just reactive care," Picking said.
If you are 50 years or older, you may be eligible for the pneumococcal and RSV vaccines, as well as a Tdap booster. The CDC also recommends a second dose of the COVID-19 vaccine for people 65 and older, and those with weakened immune systems may be eligible for an additional dose.
"It is completely normal to have questions about vaccines," Picking said. "That is exactly why your local pharmacists are here. We are easily accessible and highly trained experts, ready to provide guidance, address your concerns and help you make informed decisions about your health."
Walgreens: Your partner in health
Staying up to date with routine vaccines can seem complicated, but Walgreens makes it easy, offering the option to schedule multiple vaccines in the same visit and with flexible appointments — including same-day, nights and weekends. Walk-ins are also welcome.
Walk in or schedule ahead at Walgreens.com/ScheduleVaccine, through the Walgreens app or by calling 1-800-WALGREENS.
1 Centers for Disease Control and Prevention. "About Shingles (Herpes Zoster)." January 17, 2025.
2 Centers for Disease Control and Prevention. "Shingles Vaccination." August 19, 2025.
